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Down Syndrome 4
Part 1 of Paper
....is characterised by well-defined, distinctive
phenotypic features and natural history. An error in cell development results
in forty-seven chromosomes rather than the usual forty-six. There are three
major types of Down syndrome. About ninety-five percent of individuals with
Down syndrome have Trisomy 21. There is als.... Part 2 of Paper
....eculation of
the cause of Down syndrome. The first people to speculate that it might be
due to chromosomal abnormalities were Waardenberg and Bleyer in the
1930s. But it wasn't until 1959 that Jerome Lejeune and Patricia Jacobs,
working independently, first determined the cause to be trisomy of the 21st
chromosome. Cases of Down syndrome due to translocation and mosaicism
were described over the next three years.
The estimated incidence of Down syndrome is between 1 in 1,000 to 1
in 1,.... |
| Number of words: 1135 - Approximate pages: 5 |
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